https://completemarkets.com/Article/article-post/1623/INDOOR-AIR-QUALITY-AND-HOW-TO-IMPROVE-IT/
... as legionellosis and allergic reactions such as hypersensitivity diseases and are often documented by physical signs and laboratory findings. TOBACCO SMOKE Tobacco smoke can irritate the respiratory system. In allergic or asthmatic persons, it often results in eye and nasal irritation, coughing, wheezing, sneezing, headache, and related sinus problems. People who wear contact lenses often complain of burning, itching, and tearing eyes when exposed to cigarette smoke. Tobacco smoke is a major contributor to indoor air-quality problems. Tobacco smoke contains several hundred toxic substances. MICROORGANISMS Microorganisms and other biological contaminants (microbials) include viruses, fungi, mold, bacteria, nematodes, amoebae, pollen, dander, and mites. Sources: water-damaged materials, high-humidity indoor areas, damp organic material and porous wet surfaces, humidifiers, hot-water systems, outdoor excavations, plants, animal excreta, animals, insects, food, and food products. Acute health effects: Allergic reactions such as hypersensitivity diseases (hypersensitivity pneumonitis, humidifier fever, allergic rhinitis, etc.) and infections such as legionellosis are seen. Symptoms include chills, fever, muscle ache, chest tightness, headache, cough, sore throat, diarrhea, and nausea. MAJOR INDOOR AIR CONTAMINANTS Acetic acid Sources: X-ray development equipment, silicone caulking compounds. Acute health effects: eye, respiratory and mucous membrane irritation. Carbon dioxide Sources: unvented gas and kerosene appliances, improperly vented devices, processes or operations which produce combustion products, human respiration. Acute health effects: difficulty concentrating, drowsiness, increased respiration rate. Carbon monoxide Sources: tobacco smoke, fossil fuel engine exhausts, ...